IndraLab

Statements

USP36 increases the amount of EXOSC10. 3 / 3
| 3
reach
"As shown in Supplementary Figure S4A, knockdown of USP36 did not reduce the levels of EXOSC10 or other tested exosome core subunits including EXOSC2, EXOSC3 and EXOSC4."
36912080
reach
"Consistently, knockdown of USP36 significantly reduced the levels of EXOSC10 SUMOylation in cells by both exogenously expressed SUMO1 as determined by Ni -NTA PD assays (Figure 3C) and endogenous SUMO shown as the modified EXOSC10 band in IB assays (Figure 3D)."
36912080
reach
"To understand whether USP36-mediated SUMOylation affects EXOSC10 protein levels, we performed USP36 knockdown experiments."
36912080