IndraLab

Statements

YOD1 inhibits ERK. 3 / 3
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"YOD1 stabilizes the E3 ligase TRIM33 and inhibits the ERK/beta-catenin signaling pathway."
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"Conversely, increased YOD1 expression blocks ERK signaling by stabilizing TRIM33 activation, thereby inhibiting tumor invasion and lymph node metastasis in squamous cell carcinoma of the head and neck [25]."
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"Using the western blot, we found that YOD1 inhibited the activation of ERK and β-catenin signaling pathways in HNSCC cell lines (Fig. 4J and Supplementary Fig. 3)."
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