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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

TPR increases the amount of HCN1. 1 / 1

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"As the TPR point mutations disrupt the ability of TRIP8b (1a) and TRIP8b (1b-2) to downregulate HCN1 surface expression, we expected to observe a similar phenotype when we deleted the TPR domain of these isoforms (TRIP8b DeltaTPR)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...