IndraLab

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"For example, deletion of Cacna1c, which encodes the Cav1.2 subunit of L-type calcium channels, causes increased cell death of hippocampal neurons in knockout mice and mice harboring forebrain specific conditional knockout of Cacna1c display unusually high anxiety like behavior."

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"Moreover, Cav1.2 deletion causes cell death in adult corpus callosum within a week after recombination."