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OTUB1 activates MSH2. 2 / 2
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"To rule out the off-target effects of shRNAs, we restored the expression of OTUB1 in OTUB1-KD cells and found that OTUB1 restoration indeed efficiently increased the half-life of both MSH2 and MSH6 in these cells (XREF_FIG H)."

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"Interested in the potential mechanism of MSH2 protein regulation, Wu et al. found that OTUB1 interacts with MSH2 and increases MSH2 protein stability (Wu et al., 2021)."