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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Modified USP9X increases the amount of CTNNB1. 2 / 2

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"In MDCK cells, overexpression of the USP9X catalytic domain increased the steady-state levels of beta-catenin, presumably by its ability to deubiquitylate and hence rescue from proteasomal degradation."

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"Overexpression of Dvl, ATDC, and deubiquitinating enzyme Fam, which also affects the degradation of beta-catenin, has been reported to elevate beta-catenin level."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...