IndraLab

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Modified USP9X increases the amount of CTNNB1. 2 / 2

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"In MDCK cells, overexpression of the USP9X catalytic domain increased the steady-state levels of beta-catenin, presumably by its ability to deubiquitylate and hence rescue from proteasomal degradation."

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"Overexpression of Dvl, ATDC, and deubiquitinating enzyme Fam, which also affects the degradation of beta-catenin, has been reported to elevate beta-catenin level."

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IndraLab

Statements

Modified USP9X increases the amount of CTNNB1. 2 / 2

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