IndraLab

Statements

USP2 deubiquitinates RIPK1. 1 / 1

1 |

"We have found that the ubiquitin-specific protease <span class="match term0">USP2a</span> has a pivotal role in the decision for cell death or survival by the TNFR1 complex. This enzyme is a novel component of the TNFR1 complex that is recruited upon ligand binding and controls the signalling activity of the TNFR1-interacting protein <span class="match term1">RIP1</span> by removing its K63-linked ubiquitin chains"

22179575

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

USP2 deubiquitinates RIPK1. 1 / 1

INDRA sources:

Databases

Reading