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USP2 deubiquitinates RIPK1. 1 / 1

1 |

"?We have found that the ubiquitin-specific protease USP2a has a pivotal role in the decision for cell death or survival by the TNFR1 complex. This enzyme is a novel component of the TNFR1 complex that is recruited upon ligand binding and controls the signalling activity of the TNFR1-interacting protein RIP1 by removing its K63-linked ubiquitin chains.?"

22179575

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IndraLab

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USP2 deubiquitinates RIPK1. 1 / 1

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