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BAP1 activates cellular senescence. 2 / 2

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"Co-occurrence of BAP1 and SF3B1 mutations in uveal melanoma induces cellular senescence."

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"In a BAP1-mutated cell line olaparib plus cisplatin increased apoptosis and senescence suggesting potentiation of the effect of olaparib alone, consistent with observations in other tumor types [49] ."

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IndraLab

Statements

BAP1 activates cellular senescence. 2 / 2

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