IndraLab
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"The RANKL-UCHL1-sCD13 negative feedback loop fine-tunes osteoclastogenesis, and UCHL1 deficiency in osteoclast precursor cells disrupts this feedback loop, promoting osteoclast formation.Deubiquitinating enzymes, extensively studied in the field of bone biology, include OTUB1 , USP26 , USP34 , USP1 , and Cyld ."