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USP8 activates FZD. 1 / 1

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"Gain and loss-of-function studies showed that USP6 stabilises the membrane pool of Fzd5 and USP8 promotes the recycling of Fzd receptors to the PM, increasing their cell surface localisation and therefore enhancing Wnt signalling both in mammalian cells and Drosophila wing."

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USP8 activates FZD. 1 / 1

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