IndraLab

Statements

Reactive oxygen species inhibits NLRP3. 8 / 8
| 8
reach
"Another event required for inflammasome activation is the generation of reactive oxygen species (ROS), as most known inflammasome stimuli trigger ROS generation and treatment with various ROS scavenge[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
22921586
reach
"The administration of a non-specific reactive oxygen species scavenger, phenyl-N-tert-butylnitrone, markedly alleviated mechanical allodynia and inhibited the activation of NLRP3 inflammasome in L4-6 dorsal root ganglia and sciatic nerve of the paclitaxel-induced neuropathic pain model."
28714351
reach
"NADPH significantly reduces the level of reactive oxygen species, inhibits NLRP3 inflammasome, and effectively suppresses neuroinflammation induced by cerebral ischemia/reperfusion ( Qin et al., 2017 [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
34082063
reach
"Pretreatment of reactive oxygen species scavenger N-acetyl-L-cysteine (NAC), particularly mitochondrial reactive oxygen species scavengers Mito-TEMPO, effectively inhibited the activation of NLRP3 inflammasome, suggesting that nitrosamines could mediate the activation of NLRP3 inflammasome via mitochondrial reactive oxygen species (mtROS)."
35437791
reach
"In a study of male hyperoxaluric rats, inhibition of the transient receptor potential vanilloid 1 channel, which functions upstream of NLRP3, mitigated reactive oxygen species-induced NLRP3 activation and calcium oxalate-induced nephropathy but did not reduce hyperoxaluria ."
36329260
reach
"As an active chemical component of Astragalus mongholicus Bunge, calycosin has demonstrated its potential to significantly downregulate reactive oxygen species levels in LPS-induced bone marrow-derive[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
37164255
reach
"Li et al. demonstrated that reduced reactive oxygen species (ROS) levels and inhibited the NLRP3 signaling pathway to reduce liver damage during sepsis."
37923309
reach
"Hu et al (54) found that activation of Nrf2 signaling pathway reduced the level of reactive oxygen species in vascular endothelial cells and inhibited NLRP3 dependent endothelial cell pyrolysis."
36478888