IndraLab

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ATR phosphorylates USP28 on S67. 3 / 3
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"Here we report that the deubiquitylase USP28 is recruited to sites of DNA damage in cisplatin-treated cells. ATR phosphorylates USP28 and increases its enzymatic activity.|Representative immunoblots of n = 3. C Immunoblotting of total and phosphorylated USP28 at serine 67 and 714 in A431 cells exposed to indicated concentrations of CPPD for 6 h."

reach
"The latest research has found that ATR phosphorylates USP28 (S67 and S714) and increases its enzymatic activity, further confirming that targeting the USP28-Np63 axis in sensitizing squamous cell tones down this DNA damage response pathways [46]."

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