IndraLab

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USP22 inhibits TERT. 3 / 3
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"In retinoblastoma, the depletion of USP22 has been shown to induce cancer cell apoptosis by suppressing the TERT/P53 signal pathway ."
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"In retinoblastoma, USP22 depletion induces cancer cell apoptosis by inhibiting the TERT/P53 signaling pathway (89)."
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"USP22 can also enhance the telomerase reverse transcriptase (TERT)/p53 signaling pathway [ 65 ] and promote cell proliferation and DNA repair (see Fig. 1 )."
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