IndraLab

Statements

HTT inhibits ATXN3. 3 / 3
| 3
reach
"Our data indicate that the N-terminal fragment of polyQ-expanded (PQE) Atx7 or Htt can coaggregate with and sequester AR and Atx3 into insoluble aggregates or inclusions through their respective polyQ tracts."
37171184
reach
"PQE Atx7 and Htt reduce the soluble fraction of endogenous Atx3 but increase its insoluble aggregates."
33837238
reach
"PQE Atx7 and Htt promote proteasomal degradation of intracellular Atx3."
33837238