IndraLab

Statements

OTUD6A inhibits innate immune response. 4 / 4
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"OTUD6A Deficiency Enhances Antiviral Innate Immunity In Vivo."
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"Our data revealed that OTUD6A can both inhibit innate immunity and promote inflammatory response, highlighting its importance in accelerating the cellular response to deadly virus or bacterial infections."
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"In this study, we demonstrated that OTUD6A can attenuate the anti-virus innate immunity response and promote inflammation response.Our findings demonstrate that overexpression of OTUD6A led to the downregulation of Ifnβ expression induced by RIG-I/MAVS, cGAS/STING, TBK1/IRF3, or TRIF overexpression."
37632103
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"OTUD6A Deficiency Enhances Antiviral Innate Immunity In Vitro."
37632103