IndraLab
Statements
Thallium monochloride inhibits MYD88. 1 / 1
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1
reach
"Some of PP2Ac-target sites (XREF_SUPPLEMENTARY) that were identified based on their phosphorylation increases in TL PP2Ac depleted cells were in the components of TL specific MyD88 interactome (XREF_SUPPLEMENTARY), including Rps6 (a substrate of p70S6K), Rap1 (a MAPK component), Akt1, and a mTORC1/C2 component Raptor, revealing that through sitespecific dephosphorylation constitutively active PP2Ac represses the pro-inflammatory/-apoptotic activity of the PI3K-mTOR-p70S6K-Akt pathway."