IndraLab

Statements


USP13 activates SNAI1. 4 / 4
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"Mechanistically, USP13 knockdown promoted Snail degradation, which could be blocked by the proteasome inhibitor MG132."

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"Deubiquitinase USP13 promotes the epithelial-mesenchymal transition and metastasis in gastric cancer by maintaining Snail protein."

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"USP13 promotes migration and invasion of GC cells by maintaining the stability of Snail."

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"In conclusion, USP13 overexpression was frequently detected in GC and contributed to the EMT and metastasis of GC by stabilizing Snail."