IndraLab

Statements

OTUB1 activates cell migration. 7 / 7
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"In glioma tissues, expression of OTUB1 is increased and the expression level is associated with the glioma grade; on the other hand, knockdown of OTUB1 suppresses the tumor cell migration."
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"In the wound-healing and trans-well assays, YAP over-expression could also recover the cell migration and invasion speed, which was reduced by OTUB1 depletion in MKN28 cells (Fig. 4M, P)."
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"Cell migration and invasion exhibited a similar pattern and were also promoted by overexpression of OTUB1 (Figure 5D)."
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"In vitro study showed OTUB1 promotes gastric cancer cell migration and invasion."
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"The wound-healing assay indicated that YAP-S5A over-expression could also recover the cell migration speed, which was reduced by OTUB1 depletion in MKN28 cells (Supplementary Fig. 3H)."
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"In the wound-healing assay, YAP knockdown could also recover the cell migration speed, which was increased by OTUB1 overexpression in MKN28 cells (Supplementary Fig. 2H)."
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"In vitro wound healing and transwell assays showed that OTUB1 overexpression promoted tumor cell migration and invasion in gastric cancer cells."
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