IndraLab

Statements

USP8 activates Carcinogenesis. 8 / 8
| 1 7
reach
"Ectopic expression of USP8 promotes ESCC tumorigenesis by suppressing ID1 degradation, whereas knockdown of USP8 results in the opposite phenotypes in vitro and in vivo."
35636624
reach
"Moreover, we found that TXNIP is a novel downstream target of ID1, and USP8 promotes ESCC tumorigenesis by activating the ID1-TXNIP pathway."
35636624
eidos
"Moreover , we found that TXNIP is a novel downstream target of ID1 , and USP8 promotes ESCC tumorigenesis by activating the ID1-TXNIP pathway ."
35636624
reach
"Present findings support that USP8 gene expression levels may contribute to pitutary tumorigenesis and hormonogenesis.."
35981231
reach
"USP8 positively regulates hepatocellular carcinoma tumorigenesis and confers ferroptosis resistance through β-catenin stabilization."
37311739
reach
"Deubiquitinase USP8 increases ID1 stability and promotes esophageal squamous cell carcinoma tumorigenesis."
35636624
reach
"The data of Kasahara et al. [88] also point to a reciprocal relationship between primary cilia and cell proliferation which may provide further insights into mechanisms of tumorigenesis caused by dysregulated USP8."
31845722
reach
"Intriguingly, GLI1 is the downstream target of sonic hedgehog (SHH) signaling that is deregulated in corticotroph tumors [57] indicating that both USP8 and USP48 might trigger corticotroph tumorigenesis via the same pathway."
31845722