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USP13 activates MITF. 2 / 3
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"On the other hand, overexpression of the deubiquitinase USP13, which has been identified as a key regulator of MITF turnover, can enhance the basal half-life of the MITF protein to up to 4h (Zhao etal., 2011)."
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"More recently, it was shown that MITF is targeted by the de-ubiquitinase USP13, a theoretically drug-able protease whose suppression results in strong downregulation of MITF protein levels."
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