IndraLab

Statements

OTUD1 inhibits apoptotic process. 6 / 6
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"OTUD1 also suppresses TNF-α-induced apoptosis and necroptosis."
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"In this study, we showed that the genetic deficiency of OTUD1 accelerated the TNF-α-induced apoptosis and necroptosis, and the basal K63 ubiquitination of RIP3 was enhanced in Otud1 -MEFs (Figs."
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"OTUD1 negatively regulates the canonical NF-kappaB activation, apoptosis, and necroptosis, whereas OTUD1 upregulates the interferon (IFN) antiviral pathway."
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"OTUD1 suppresses TNF-alpha-induced apoptosis and necroptosis."
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"OTUD1 Inhibits Apoptosis of Fibroblast."
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"Cell samples were stained and incubated with Annexin V and PI, the apoptosis rate of the si-OTUD1 group was significantly higher than that of the NC group (P < 0.05, Figure 7B) according to the results of the flow cytometry assay (Figure 7A), demonstrating that OTUD1 gene can significantly inhibit fibroblast apoptosis."
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