IndraLab
Statements
eidos
"The new findings of the study are that ( i ) STAMBP modulates inflammasome activation and IL-1beta secretion in monocytes , ( ii ) NLRP3 , through its deubiquitination by STAMBP , represents a new client for the DUB , and ( iii ) NLRP3 K-63 linked polyubiquitination triggered by STAMPB cellular depletion appears to modulate inflammasome activity but not by increasing NLRP3 protein abundance ."