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Cloxyquin activates KCNK18. 6 / 6
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"Indeed, due to its expression in the dorsal root ganglion a novel TRESK activator could also be of major therapeutic interest in the treatment of neuropathic pain and other nociceptive disorders.In co[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Cloxyquin activates TRESK in its resting state, by a mechanism independent of Ca /calcineurin-mediated dephosphorilation."

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"Cloxyquin activates TRESK by a Ca 2+ / calcineurin independent mechanism."

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"Cloxyquin activates K2P18.1 ( TRESK ) [ 234 ] ."

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"Although limited pharmacological characterization has been performed to date, these data are compelling evidence that Cloxyquin is able to increase TRESK activity.The aim of this work was to identify [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Cloxyquin selectively activates TRESK and not other K2P channels (Lengyel et al., 2017)."