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Modified SOX5 increases the amount of CACNA1D. 2 / 2

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"Taken together, the human data corroborate the observations in INS-832/13 cells and rodent islets, showing that SOX5 overexpression induces expression changes opposite to that of T2D islets, increases CACNA1D expression and improves beta-cell function in T2D islets."

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"Moreover, SOX5 overexpression increased the expression of CACNA1D mRNA (P = 0.007; XREF_FIG)."

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IndraLab

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Modified SOX5 increases the amount of CACNA1D. 2 / 2

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