IndraLab

Statements

COPS5 activates BRR2. 4 / 4
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reach
"The Jab1 and MPN domain of Prp8 increases the unwinding activity of Brr2 invitro."
23727230
reach
"Jab1 mediated activation of Brr2 is apparently crucial for efficient U4/U6 disruption during spliceosome activation."
27792457
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"One possible mechanism how the Jab1 and MPN domain activates Brr2 could be releasing the brake imposed by the HLH domain."
23727230
reach
"It has been shown that the Jab1 and MPN domain enhances the unwinding activity of Brr2."
23727230