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AICA ribonucleotide inhibits CASP1. 2 / 2

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"AICAR and salicylate inhibited NLRP3 induction and caspase-1 activation, and as a result, IL-1beta secretion was reduced."

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"Moreover, AICAR could also abolish alpha-Syn-induced activation of caspase-1 (Additional file 3 : Figure S3f) and the increase of IL-1beta production (Additional file 3 : Figure S3g)."

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IndraLab

Statements

AICA ribonucleotide inhibits CASP1. 2 / 2

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