Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

SKP2 activates USP18. 3 / 4

| 3

➶

reach

"Patient fibroblasts, transduced with control luciferase (Luc) or with USP18, were treated with IFNalpha and SKP2 was immunoprecipitated."

30858391

➶

reach

"SKP2 (S-phase kinase associated protein 2) was found to target USP18 to ubiquitination and proteosomal degradation 10."

30858391

➶

reach

"As summarized above, SKP2 can target USP18 for degradation, while ISG15 has an opposite action, being required for accumulation of USP18 as seen in IFN stimulated cells."

30858391

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

Other Services

This Service

This Project

IndraLab

Statements

SKP2 activates USP18. 3 / 4

Our Sources:

Databases

Reading