IndraLab

Statements

USP15 binds FHL1. 11 / 11
2 | 3 6
sparser
"We have shown that USP15 interacts physically and functionally with SLIM1, and stabilizes SLIM1 by deubiquitination in the transient expression system in HEK293T cells."
21219870
reach
"Thus, the protein levels of SLIM1 are regulated by the Ub-proteasomal system, and USP15 interacts physically and functionally with SLIM1 in mammalian cells.The above results suggest that USP15 may hav[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
21219870
sparser
"As shown in Fig. 1 B, purified recombinant USP15 and SLIM1 were also bound to each other under cell-free conditions, indicating that the interaction is direct."
21219870
sparser
"In an effort to find novel protein–protein interactions by computational prediction (to be reported elsewhere) and its biochemical confirmation, we have identified a novel interaction of USP15 with SL[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
21219870
reach
"We have shown that USP15 interacts physically and functionally with SLIM1, and stabilizes SLIM1 by deubiquitination in the transient expression system in HEK293T cells."
21219870
sparser
"In the present study, we have shown that USP15 interacts with SLIM1 and deubiquitinates SLIM1, leading to the stabilization of SLIM1."
21219870
sparser
"Furthermore, USP15C269S, a catalytic-inactive USP15 mutant [16] was unable to bind with SLIM1, suggesting that the region around C269, the core enzymatic domain, was critical for the interaction."
21219870
biogrid
No evidence text available
21219870
sparser
"Thus, the protein levels of SLIM1 are regulated by the Ub-proteasomal system, and USP15 interacts physically and functionally with SLIM1 in mammalian cells."
21219870
reach
"In the present study, we have shown that USP15 interacts with SLIM1 and deubiquitinates SLIM1, leading to the stabilization of SLIM1."
21219870
biogrid
No evidence text available
21219870