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OTUB2 activates RD21A. 5 / 5
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"Transient expression of PbE3‐2‐GFP, RD21A‐FLAG and OTU2‐Myc in N. benthamiana revealed that OTU2 increased RD21A accumulation compared to the control with an empty vector (Figure S3a), suggesting that OTU2 may protect RD21A from degradation mediated by PbE3‐2."

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"To determine whether OTU2 increases RD21A protein accumulation in A. thaliana, we performed immunoblot analysis using an anti‐RD21A antibody."

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"Considering that OTU2 increases RD21A accumulation, we hypothesized that OTU2 overexpression increases plant resistance against pathogens."

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"OTU2-mediated resistance enhancement requires RD21A ."

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"Further experiments are required to elucidate how OTU2 modulates RD21A stability in the absence of pathogen invasion and whether additional regulatory factors are involved in this process."