IndraLab

Statements

MYOD1 increases the amount of USP2. 4 / 4
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"Taken together, these findings demonstrate that MYOD1 transcriptionally activates USP2 expression by binding to its promoter region."
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"MYOD1 activates USP2 transcription by binding to its promoter region."
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"Hence, we first determined whether MYOD1 regulates USP2 expression in C2C12 cells and found that Myod1 overexpression increased, whereas Myod1 knockdown inhibited Usp2 protein levels in C2C12 cells (Fig. 8C)."
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"Additionally, MYOD1 induces the transcription of USP2, which is downregulated during muscle atrophy."
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