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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Sensor activates KCNMA1. 2 / 2

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"We isolated the effect of Ca 2+ binding on voltage sensor activation from its effect on channel opening by taking advantage of the fact that C-O transition kinetics are much slower than voltage sensor activation in Slo1 channels."

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"This scheme is analogous to the postulated mechanisms of coupling of voltage sensor activation and Ca 2+ binding in the BK channel in which the interaction occurs only in the same subunit."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...