IndraLab

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Modified USP8 decreases the amount of SMO. 1 / 1
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reach
"The overexpression of USP8 decreased the amount of Smo that co-localized with Rab5 (XREF_FIG), which suggested that USP8 may prevent the accumulation of Smo in early endosomes and therefore promote the cell surface accumulation of the protein (XREF_FIG) as well as increase the signaling activity (XREF_FIG)."