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COPS6 activates CRC PDOs. 2 / 2
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reach
"We found that decreasing CSN6 expression via knockdown reduced the number and growth of CRC PDOs, supporting the role of CSN6 in regulating stemness during tumorigenicity."

eidos
"Knockdown of CSN6 reduced the number and the size of CRC PDOs formed ( Fig. 1g ) ."