IndraLab

Statements

YAP1 increases the amount of USP40. 3 / 3
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"YAP mediated the tumor-promoting role of USP40 and transcriptionally activated USP40 expression in HCC."
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"Next, we confirmed that YAP overexpression increased USP40 expression in HCCLM3 and PLC/PRF/5 cells (P < 0.05, Fig. 6 A and B and Supplementary Fig. 5A )."
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"Otherwise, YAP-TEAD inhibitor (Verteporfin) and YAP knockdown consistently reduced USP40 level in HCC cells (P < 0.05, Fig. 6 C–F and Supplementary Fig. 5B )."
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