IndraLab

Statements

SCN1A activates sodium atom. 5 / 5
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"Dravet syndrome (DS) is an infantile epileptic encephalopathy mainly caused by de novo mutations in the SCN1A gene encoding the alpha1 subunit of the voltage gated sodium channel Na v 1.1."
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"Scn1a null mice have increased Na v 1.3 expression in the hippocampus [XREF_BIBR]."
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"Dravet syndrome is a devastating infantile-onset epilepsy syndrome with cognitive deficits and autistic traits caused by genetic alterations in SCN1A gene encoding the alpha-subunit of the voltage gated sodium channel Na v 1.1."
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"Dravet syndrome (DS) is a childhood epilepsy syndrome caused by heterozygous mutations in the SCN1A gene encoding voltage gated sodium channel Na v 1.1."
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"SCN1A haploinsufficiency producing Na V 1.1 dysfunction mainly affects GABAergic neurons."
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