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RHBDF2 inhibits EIF3F. 1 / 1

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"For instance, iRhom2 could regulate the stability of PLC or other proteins involved in the MHC-I antigen presentation pathway, in a similar manner to its regulation of ubiquitination and therefore stability of STING and VISA [15, 16] Indeed, iRhom2 prevents proteasomal degradation of STING by recruiting the deubiquitinase EIF3S5 that removes K48-linked polyubiquitin chains from the protein."

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RHBDF2 inhibits EIF3F. 1 / 1

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