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USP51 deubiquitinates Parkinson Disease on lysine. 2 / 2
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"In addition, three deletion constructs of PD‐L1‐C were generated to demonstrate that the deletion variant PD‐L1‐C3, but not PD‐L1‐C1 and PD‐L1‐C2, was able to interact with USP51 (Figure 5E), highlighting that the PD‐L1C‐terminal region (280‐290aa) is critical for the USP51‐PD‐L1 association.Next, we examined whether USP51 could deubiquitinate the lysine residues of PD‐L1‐C3."
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"Indeed, USP51 was able to deubiquitinate PD‐L1 at either K280 or K281 lysine residue (Figure 5H)."
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