IndraLab

Statements

N-tosyl-L-phenylalanyl chloromethyl ketone inhibits IKBKB. 2 / 2
| 1 1
reach
"These results suggest that TPCK inhibits NF-kappaB activation by directly modifying thiol groups on two different targets : Cys 179 of IKKbeta and Cys 38 of p65 and RelA."
19591457
trips
"Our data reveals for the first time that PDK1 and PKB may differentially activate NF-kappaB, and that TPCK may subserve a useful anti-inflammatory function by inhibiting IKKbeta."
17136479