IndraLab

Statements

USP9X activates SOX2. 3 / 3
| 1 2
eidos
"Usp9x knockdown , as well as inhibition with DUB inhibitor , G9 , blocked SOX2 expression , suppressed in vitro colony growth , and induced apoptosis of BRAF-mutant melanoma cells ."
33613844
reach
"Exogenous overexpression of Usp9x in SK-Mel29 cells lead to upregulation of SOX2 (XREF_FIG) and as expected, increased 3D tumor growth (XREF_FIG)."
33613844
reach
"MG132 treatment reversed the reduction of SOX2 by Usp9x KD, indicating that ubiquitin proteasome pathway plays a role in controlling SOX2 levels (XREF_FIG)."
33613844