IndraLab

Statements


USP4 activates INS. 2 / 2
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reach
"Liver-specific USP4 overexpression increased insulin sensitivity and attenuated steatosis and inflammatory injury."

reach
"Furthermore, gastrodin significantly upregulated the expression of USP4 and increased the binding of USP4 to the insulin receptor.Considering the importance of the PI3K-Akt pathway in the pathogenesis of T2DM, we detected the effects of gastrodin on the PI3K-Akt pathway to further explore the underlying mechanism of gastrodin in ameliorating insulin resistance."