IndraLab

Statements


USP22 inhibits MTOR. 3 / 3
| 3

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"USP22 reduces the mTOR activity to retard the progression of CRC[8]."

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"USP22 prevents ubiquitination-mediated EGFR degradation, thereby inducing persistent activation of EGFR-mediated oncogenic signaling pathways, such as STAT3, AKT/mTOR, and MEK/ERK pathways."

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"USP22 knockdown protects against cerebral ischemia/reperfusion injury via destabilizing PTEN protein and activating the mTOR/TFEB pathway."