IndraLab

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IFNL4 activates USP18. 2 / 2

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"IFN-alpha unresponsiveness depends on ISG15 and USP18 in cells that overexpress IFN-lambda4 or treated with IFN-lambda4."

28630501

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"Microarray analysis revealed that IFN-lambda4 could induce ubiquitin specific peptidase 18 (USP18), a known inhibitor of the type I IFN signalling pathway, in a more sustained pattern compared with type I interferon induction."

27302182

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IndraLab

Statements

IFNL4 activates USP18. 2 / 2

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