IndraLab

Statements

KCNA3 phosphorylates LEP. 2 / 2
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"Insulin-induced Kv1.3 phosphorylation in the OB (Fadool and Levitan, xref ; Fadool et al., xref ) was lost in DIO mice (Marks et al., xref ) and slices from these mice exhibited loss of insulin modulation of mitral cell excitability, exemplifying a degree of insulin resistance for mitral cell function in the obese state (Fadool et al., xref )."
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"Specifically, a single dose of IND increased Kv1.3 phosphorylation in the OB, resulting in current suppression with effects similar to that observed in Kv1.3-knockout mice [ xref ]."
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