IndraLab

Statements


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"STAT1 is implicated in the mediation of Ang II-induced human glomerular mesangial cell senescence through the p53/p21(Cip1) pathway, and losartan could attenuate this senescence by regulating STAT1 [26]."

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"Losartan inhibits STAT1 activation and protects human glomerular mesangial cells from angiotensin II induced premature senescence."

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"Our results indicate that STAT1 is implicated in the mediation of Ang II induced HMC senescence through p53 / p21 (Cip1) pathway, and that losartan could attenuate HMC senescence by regulating STAT1."