IndraLab

Statements

AKT phosphorylates USP43. 3 / 3
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sparser
"Under high glucose, AKT phosphorylates USP43, promoting its binding to 14-3-3β/ε and weakening USP43-HSPA8 interaction."
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rlimsp
"Interestingly, USP43 also exists in the cytoplasm, where it is phosphorylated by AKT, enabling its binding to the 14-3-3β/ε heterodimer and sequestration in the cytoplasm."
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sparser
"He and colleagues have shown that USP43 is phosphorylated by AKT in breast cancer cells (Fig.  xref A), which triggers its binding to 14-3-3β/ε and subsequent retention in the cytoplasm [ xref ]."
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