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Pioglitazone activates KCNQ1. 2 / 2

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"KCNQ1 and H +/K +-ATPase protein abundance in the parietal cell membrane was enhanced by pioglitazone treatment in sgk1 +/+ but not in sgk1-/- mice."

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"In conclusion, pioglitazone increases gastric acid secretion, an effect at least partially due to stimulation of SGK1 expression and SGK1 dependent upregulation of KCNQ1."

19710534

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Pioglitazone activates KCNQ1. 2 / 2

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