IndraLab

Statements

JOSD1 binds SOCS1. 7 / 8
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"Co-immunoprecipitation assay further shows that endogenous SOCS1 interacts with ectopically expressed JOSD1 both in HepG2 and primary mouse hepatocytes (Fig. xref )."
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"Also, the functional role of the JOSD1–SOCS1 axis in human subjects is to be investigated."
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"In Duck Tembesu virus infection, JOSD1 interacts with SOCS1 via its SH2 domain and stabilises SOCS1."
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"JOSD1 interacts with and deubiquitinates SOCS1 to mitigate apoptosis under proteotoxic stress."
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"JOSD1 physically interacts with SOCS1, which is an essential negative regulator of many cytokines signaling, and enhances SOCS1 stability by deubiquitinating K48-linked polyubiquitination of SOCS1."
28355105
sparser
"In Duck Tembesu virus infection, JOSD1 interacts with SOCS1 via its SH2 domain and stabilises SOCS1."
39284830
reach
"JOSD1 physically interacts with SOCS1, which is an essential negative regulator of many cytokines signaling, and enhances SOCS1 stability by deubiquitinating K48 linked polyubiquitination of SOCS1."
28355105