IndraLab

Statements

USP1 inhibits cell population proliferation. 6 / 6
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"Depletion of Usp1 decreases epidermal proliferation in Fancd2 (+/-) mice."
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"The proliferation of GSCs is suppressed by depletion of β-catenin, USP1 or EZH2, which is rescued by overexpression of EZH2 K421R/Y641F mutant."
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"Thus, we made a conclusion that targeting USP1 could reduce the proliferation of HCC cells.4 DISCUSSION."
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"USP1 downregulation decreased expressions of fibrosis related genes, suppressed proliferation, and promoted apoptosis in TGF-beta1-induced LX-2 cells, which were reversed by SNAIL overexpression."
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"Targeting USP1 could decrease the proliferation of HCC cells via cell cycle arrest."
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"Collectively, our results suggest that silencing USP1 inhibits cell proliferation and invasion in U2OS cells."
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