IndraLab

Statements

Sirolimus inhibits IFNB1. 4 / 4
| 4
reach
"Rapamycin additionally diminished the IFNbeta response to CpG-A and CpG-B in DNA-PKcs- or DNA-PKcs and Ku70-deficient BMDCs (XREF_FIG)."
25812014
reach
"As shown in XREF_FIG, both anti--IFNAR2 antibody and rapamycin inhibited IFNbeta induction of OAS2 RNA; inhibition by anti--IFNAR2 was rapid (within 24 h), while inhibition by rapamycin was only evident at 72 hr."
28107341
reach
"Rapamycin also significantly inhibited pDC secretion of IFN-beta, TNF and IL-6 (XREF_FIG and XREF_SUPPLEMENTARY online)."
18758466
reach
"Including rapamycin increased the survival of established tumor bearing mice, as rapamycin treatment reduced the local IFNb production."
23726825