IndraLab

Statements


JOSD2 deubiquitinates YAP1. 3 / 3
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"JOSD2 has been shown to promote cholangiocarcinoma progression by deubiquitinating and stabilizing YAP/TAZ16."

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"The tumor-promoting effects were also revealed by another study that JOSD2 deubiquitinates and stabilizes YAP/TAZ by cleaving their proteolytic ubiquitination and inhibiting the latter degradation in cholangiocarcinoma."

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"Our previous study revealed the pro-tumor function of JOSD2 in cholangiocarcinoma and found that JOSD2 deubiquitinates and stabilizes YAP/TAZ by cleaving the proteolytic ubiquitination and inhibiting the latter degradation."